تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
Assessment of biochemical and antioxidative status in patients suffering from dengue fever
Assessment of biochemical and antioxidative status in patients suffering from dengue fever
 
لغة الوثيقة : الانجليزية 
المستخلص : A multi-centred study was designed to collect dengue epidemiologic data from government and registered private hospitals/clinics and maintained archive of frozen specimens in bio-bank to be used for future dengue epidemic control program, and assess the epidemiology of dengue fever (DF) by evaluating biochemical and oxidative status of patients. ELISA IgM antibodies test was done to confirm DF. From August 2010 to December 2011, 101 confirmed blood samples of DF patients referred to pathology lab of Jinnah Hospital Lahore were subjected to the epidemiologic assessment by evaluating the biochemical and physiological indices and alterations of circulating antioxidants. Clinical features of DF patients and effect of fever on blood components and serum proteins of liver were recorded. The hospital stay in DF, dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) showed significant difference. Significant increases in serum alanine amino transferase (ALT) (P=0.000), aspartate amino transferase (AST) (P=0.000), alkaline phosphatase (ALP) (P=0.000), malondialdehyde (MDA) along with significant decreases in total protein (TP) (P=0.000), reduced glutathione (GSH) (P=0.000), superoxide dismutase (SOD), catalase (CAT) (P=0.000), and sialic acid contents (P=0.016) were observed. A positive correlation existed between bound sialic acid levels, liver enzymes and circulating antioxidants (r=0.656, P=0.016). In the present study, alterations of circulating antioxidants in DF suggest that DF might be a metabolic response to an acute, self-limiting tropical viral infection, and a consequence of the viral inflammatory process. 
ردمد : 1672-0733 
اسم الدورية : J Huazhong Univ Sci Technolog Med Sci 
المجلد : 35 
العدد : 3 
سنة النشر : 1436 هـ
2015 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Wednesday, April 27, 2016 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
Mahmood RasoolRasool, Mahmood باحث رئيسي mahmoodrasool@yahoo.com
Arif MalikMalik, Arif باحث مشارك  
Khalid Mahmud KhanKhan, Khalid Mahmudباحث مشارك  
Muhammad Saeed QureshiQureshi, Muhammad Saeedباحث مشارك  
Beenish ShabbirShabbir, Beenish باحث مشارك  
Sara ZahidZahid, Sara باحث مشارك  
Muhammad AsifAsif, Muhammad باحث مشارك  
Abdul MananManan, Abdul باحث مشارك  
Sana RashidRashid, Sana باحث مشارك  
Saima Rubab KhanKhan, Saima Rubabباحث مشارك  
Hafiz Muhammad ArsalanArsalan, Hafiz Muhammadباحث مشارك  
Rabail AlamAlam, Rabail باحث مشارك  
Mahwish AroojArooj, Mahwish باحث مشارك  
Mahmood Husain QaziQazi, Mahmood Husainباحث مشارك  
Adeel Gulzar Ahmed ChaudharyChaudhary, Adeel Gulzar Ahmedباحث مشارك  
Adel Mohammed AbuzenadahAbuzenadah, Adel Mohammedباحث مشارك  
Mohammed Hussain Al-QahtaniAl-Qahtani, Mohammed Hussainباحث مشارك  
Sajjad KarimKarim, Sajjad باحث مشارك  

الملفات

اسم الملفالنوعالوصف
 38716.pdf pdf 

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